Benjamin Chandler

Graduate Student

Biography

I graduated from the University of Michigan with a double major in Biology and Biomedical Sciences in 2013. In undergraduate I performed research on a long non-coding RNA (lncRNA), SChLAP1, and its role in prostate cancer. Following undergraduate I work as a lab tech and continued my work on characterizing SChLAP1. Currently, I work in Corey Speers lab studying lncRNAs and their role in basal-like breast cancer. When not in lab I can usually be found on the golf course!!

Research Interests

I am interested in characterizing lncRNAs found in breast cancer. Through RNA sequencing techniques many novel lncRNAs have been nominated to play a role in breast cancer. I am currently studying lncRNAs specifically up-regulated in basal-like breast cancer.

Publications

Prensner JR, Sahu A, Iyer MK, Malik R, Chandler B, Asangani I, Poliakov A, Vergara I, Alshalalfa M, Jenkins R, Davicioni E, Feng F, Chinnaiyan AM. The lncRNAsPCGEM1 and PRNCR1 are not implicated in castration resistant prostate cancer. Oncotarget, 5(6), 1434-1438 (2014).

Presner JR, Iyer MK, Sahu A, Asangani I, Cao Q, Pate L, Vergara I, Davicioni E, Erho N, Ghadesssi M, Jenkins R, Triche T, Malik R, Bedenis R, McGregor N, Ma T, Chen W, Han S, Jing X, Cao X, Wang X, Chandler B, Yan W, Siddiqui J, Kunju L, Dhanasekaran SM, Pienta K, Fend F, Chinnaiyan AM. The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex. Nature Genetics 45, 1392–1398 (2013).

Balbin OB, Presner JR, Sahu A, Yocum A, Shankar S, Majik R, Fermin D, Dhanasekaran SM, Chandler B, Thomas D, Beer DG, Cao X, Nesvizhskii AI, Chinnaiyan AM. Reconstructing targetable pathways in lung cancer by integrating diverse omics data. Nature Communications 4, 2617 (2013).

 

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