Christie Rodriguez Ramirez
Christie received a Bachelor’s in Science degree in Industrial Biotechnology from the University of Puerto Rico- Mayagüez. There she worked in the laboratory of Dr. O.M. Suarez and Dr. Oscar Perales studying metallurgy and the synthesis and functionalization of nanoparticles for biomedical applications. Upon completion of her B.S., she accepted a postbaccalaureate fellowship at The Mayo Clinic where she worked in the laboratory of Dr. Karen Hedin studying CXCR4 signaling in Acute Myeloid Leukemia. Christie entered the PIBS program in the fall of 2014 and was awarded a Rackham Merit Fellowship. She is currently working under her thesis mentor Dr. Jacques Nör on salivary gland cancer stem cells.
Christie is interested in studying the interaction between p53 and Wnt in mucoepidermoid carcinoma stem cells.
Clift, I.C., Bamidele, A.O., Rodriguez-Ramirez, C., Kremer, K.N., Hedin, K.E. (2014). “β-arrestin1 and distinct CXCR4 structures are required for SDF-1 to down-regulate CXCR4 cell-surface levels in neuroblastoma.” Mol Pharm (published before print). doi:10.1124/mol.113.089714
Kremer, K.N. et al. (2013). “SDF-1/CXCR4 signaling induces apoptosis in acute myeloid leukemia cells via regulation of the Bcl- 2 family members Bcl-XL, Noxa, and Bak”. J Biol Chem, 288(32), 22899-914. PMID: 23798675