Daysha Ferrer-Torres

Graduate Student

Biography

Daysha Ferrer-Torres B.S. is a PhD candidate in the Department of Cancer Biology at the University of Michigan. She has received her bachelor’s degree at the University of Puerto Rico in Mayaguez, and has been the recipient of a number of distinguished awards including the Sloan undergraduate minority research award. During this time, she also undertook collaborative work at the National Cancer Institute working with epidemiologist Dr. Cheryl Winkler. Daysha, a Rackham Merit Fellow, is currently the recipient of the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship. She is under the guidance of Dr. David G. Beer where she is working towards understanding of the molecular basis of Esophageal Adenocarcinomas (EAC): more specifically, identifying biomarkers that can stratify individuals by risk of disease, and the molecular differences in the incidence of EAC between African Americans and Caucasian populations.

Research Interests

Molecular understanding of Esophageal Cancer; Biomarker detection; Prevention and early diagnostic methods for patients at risk for Barrett’s Esophagus and Esophageal Adenocarcinomas.

Publications

1. Daysha Ferrer-Torres, Derek J. Nancarrow, Rork Kuick, Dafydd Thomas, Ernest Nadal-Alforja, Jules Lin, Andrew Chang, Rishindra Reddy, Mark B. Orringer, Jeremy M. G. Taylor, Thomas D. Wang and David G. Beer Genomic Similarity between Gastroesophageal Junction and Esophageal Barrett’s Adenocarcinomas. Oncotarget. Jul 2016 DOI: 10.18632/oncotarget.10253

2. Shen YC, Upadhyayula R, Cevallos S, Messick RJ, Hsia T, Leese MP, Jewett DM, Ferrer-Torres D, Roth TM, Dohle W, Potter BV, Barald KF. Targeted NF1 cancer therapeutics with multiple modes of action: small molecule hormone-like agents resembling the natural anticancer metabolite, 2-methoxyoestradiol. Br J Cancer. 2015 Oct 20;113(8):1158-67. doi: 10.1038/bjc.2015.345. Epub 2015 Oct 13. PubMed PMID: 26461061.

3. Myers AL, Lin L, Nancarrow DJ, Wang Z, Ferrer-Torres D, Thomas DG, Orringer MB, Lin J, Reddy RM, Beer DG, Chang AC. IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma. Oncotarget. 2015 Sep 22;6(28):25897-916. doi: 10.18632/oncotarget.4532. PubMed PMID: 26317790.

4. Lin J, Myers AL, Wang Z, Nancarrow DJ, Ferrer-Torres D, Handlogten A, Leverenz K, Bao J, Thomas DG, Wang TD, Orringer MB, Reddy RM, Chang AC, Beer DG, Lin L. Osteopontin (OPN/SPP1) isoforms collectively enhance tumor cell invasion and dissemination in esophageal adenocarcinoma. Oncotarget. 2015 Sep 8;6(26):22239-57. PubMed PMID: 26068949.

5. Stachler MD, Taylor-Weiner A, Peng S, McKenna A, Agoston AT, Odze RD, Davison JM, Nason KS, Loda M, Leshchiner I, Stewart C, Stojanov P, Seepo S, Lawrence MS, Ferrer-Torres D, Lin J, Chang AC, Gabriel SB, Lander ES, Beer DG, Getz G, Carter SL, Bass AJ. Paired exome analysis of Barrett's esophagus and adenocarcinoma. Nat Genet. 2015 Sep;47(9):1047-55. doi: 10.1038/ng.3343. Epub 2015 Jul 20. PubMed PMID: 26192918; PubMed Central PMCID: PMC4552571.

6. Leicht DT, Kausar T, Wang Z, Ferrer-Torres D, Wang TD, Thomas DG, Lin J, Chang AC, Lin L, Beer DG. TGM2: a cell surface marker in esophageal adenocarcinomas. J Thorac Oncol. 2014 Jun;9(6):872-81. doi: 10.1097/JTO.0000000000000229. PubMed PMID: 24828664; PubMed Central PMCID: PMC4170218.

7. Nadal E, Chen G, Gallegos M, Lin L, Ferrer-Torres D, Truini A, Wang Z, Lin J, Reddy RM, Llatjos R, Escobar I, Moya J, Chang AC, Cardenal F, Capellà G, Beer DG. Epigenetic inactivation of microRNA-34b/c predicts poor disease-free survival in early-stage lung adenocarcinoma. Clin Cancer Res. 2013 Dec 15;19(24):6842-52. doi: 10.1158/1078-0432.CCR-13-0736. Epub 2013 Oct 15. PubMed PMID: 24130071; PubMed Central PMCID: PMC4161219.

Stachler MD, Taylor-Weiner A, S Peng, A McKenna, I Leshchiner, C Stewart, P Stojanov, S Chauvin, MS Lawrence, D Ferrer Torres, J Lin, A Chang, SB Gabriel, ES Lander, DG Beer, SL Carter, G Getz, AJ Bass. Paired exome analysis of Barrett’s esophagus and adenocarcinoma reveals distinct paths to cancer. Nat. Genet.
Nat Genet 2015 Jul 20. Epub 2015 Jul 20.

Jules Lin, Amy L Myers, Zhuwen Wang, Derek J Nancarrow, Daysha Ferrer-Torres, Amy Handlogten, Kimmy Leverenz, Julia Bao, Dafydd G Thomas, Thomas D Wang, Mark B Orringer, Rishindra M Reddy, Andrew C Chang, David G Beer, Lin Lin. Osteopontin (OPN/SPP1) isoforms collectively enhance tumor cell invasion and dissemination in esophageal adenocarcinoma. Oncotarget 2015 Jun 1. Epub 2015 Jun 1.

 

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