David Beer, Ph.D.
John and Carla Klein Professor of Thoracic Surgery
David G. Beer is Professor of Surgery and Professor of Radiation Oncology at the University of Michigan. He received a Ph.D. in biochemical pharmacology at University of Colorado at Boulder in 1984 and completed post-doctoral training in molecular oncology at the McArdle Laboratory for Cancer Research, University of Wisconsin, Madison. In 1987 Dr. Beer became an Assistant Professor in Pharmacology, Toxicology and Therapeutics at the University of Kansas Medical School in Kansas City, KS. In 1991 he joined the faculty at the University of Michigan Medical School in Ann Arbor. Dr. Beer is Co-Director of the Cancer Genetics Program for the University of Michigan Rogel Comprehensive Cancer Center.
Current research involves understanding the role of RNF128, a E3 ubiquitin ligase, in regulating the stability and function of wildtype and mutant TP53 in Barrett's metaplasia and its progression to esophageal adenocarcinoma; RNAseq of Barrett's, low-grade dysplasia, high-grade dysplasia and cancer to identify and develop cell surface markers that can be utilized for endoscopic early detection strategies; developing new multi-objective machine learning algorithms for analyzing large-scale genomic data of common human diseases, which will improve the reproducibility and clinical impact of computational methods for precision medicine.